Publicado 2025-03-05
Palabras clave
- Addiction,
- Disease,
- Impaired Behavioral Control,
- Dysfunction,
- Harm
- Adicción,
- Enfermedad,
- Control conductual deteriorado,
- Disfunción,
- Daño

Esta obra está bajo una licencia internacional Creative Commons Atribución-NoComercial 4.0.
Resumen
En este artículo, echo una mirada al debate acerca del estatus de la adicción como enfermedad. Aunque la adicción es comúnmente vista como una enfermedad, varios autores han esgrimido razones para el agnosticismo o el escepticismo acerca de la corrección de esta etiqueta. Cualquier intento de abordar esta discusión directamente se complica por su relación con varios otros debates abiertos, tanto del lado de las teorías de la adicción como del lado de las teorías de la enfermedad. Mi objetivo principal en este artículo es identificar cuáles son los principales puntos de controversia. Mi objetivo secundario es ofrecer una defensa limitada de la tesis de la adicción como enfermedad. El punto neurálgico del debate es si la adicción es el resultado de una disfunción psicológica, y el principal obstáculo para afirmar que hay tal disfunción psicológica es que actualmente carecemos de una explicación relativamente unificada del rasgo conductual que más fuertemente sugiere la ocurrencia de algo disfuncional: la merma de la capacidad esperable para controlar la propia conducta. Según sostengo, hay un sentido en el que la afirmación de disfunción puede estar justificada incluso en ausencia de una explicación causal unificada. Esto requiere, sin embargo, suposiciones que son hasta cierto punto controversiales, incluyendo la visión de la adicción en términos de deterioro del control conductual y la aceptabilidad de predicar disfunción a partir de rasgos conductuales a nivel personal.
Citas
- Ainslie, G. (2000). A research-based theory of addictive motivation. Law & Philosophy, 19, 77-115. http://www.jstor.org/stable/3505175
- American Psychiatric Association (2022). Diagnostic and statistical manual of mental disorders: DSM-5-TR. American Psychiatric Association.
- Amundson, R. (2000). Against normal function. Studies in History and Philosophy of Science Part C: Studies in History and Philosophy of Biological and Biomedical Sciences, 31(1), 33-53. https://doi.org/10.1016/S1369-8486(99)00033-3
- Barnett, A., Savic, M., Pickersgill, M., O’Brien, K., Lubman, D. I., & Carter, A. (2022). Addiction treatment providers’ engagements with the brain disease model of addiction. In N. Heather, M. Field, A. C. Moss, & S. Satel (Eds.), Evaluating the brain disease model of addiction (pp. 283-294). Routledge. http://doi.org/10.4324/9781003032762-30
- Becker, G., & Murphy, K. (1988). A theory of rational addiction. Journal of Political Economy, 96(4), 675-700. https://doi.org/10.1086/261558
- Berridge, K. C. (2017). Is addiction a brain disease? Neuroethics, 10(1), 29-33. https://doi.org/10.1007/s12152-016-9286-3
- Boorse, C. (1975). On the distinction between disease and illness. Philosophy & Public Affairs, 5(1), 49-68. http://www.jstor.org/stable/2265020
- Boorse, C. (2014). A second rebuttal on health. Journal of Medicine and Philosophy, 39(6), 683-724. https://doi.org/10.1093/jmp/jhu035
- Bortolotti, L. (2020). Doctors without ‘disorders.’ Aristotelian Society Supplementary Volume, 94(1), 163-184. https://doi.org/10.1093/arisup/akaa006
- Burdman, F. (2022). A pluralistic account of degrees of control in addiction. Philosophical Studies, 179(1), 197-221. https://doi.org/10.1007/s11098-021-01656-7
- Burdman, F. (2024). Recalcitrant desires in addiction. In S. Amaya, D. Shoemaker, & M. Vargas (Eds.), Oxford Studies in Agency and Responsibility, vol. 8 (pp. 58-80). Oxford University Press. https://doi.org/10.1093/oso/9780198910114.003.0004
- Carter, A., Mathews, R., Bell, S., Lucke, J., & Hall, W. (2014). Control and responsibility in addicted individuals: What do addiction neuroscientists and clinicians think? Neuroethics, 7(2), 205-214. https://doi.org/10.1007/s12152-013-9196-6
- Connelly, M., Malato, D., Benz, J., Rein, D., Emery, S., Meit, M., Oppenheimer, C., Tompson, T., Kantor, L., Ganesh, N., & Swanson, E. (2018). Americans recognize the growing problem of opioid addiction. The Associated Press-NORC Center for Public Affairs Research.
- Cooper, R. (2020). The concept of disorder revisited: Robustly value-laden despite change. Aristotelian Society Supplementary Volume, 94(1), 141-161. https://doi.org/10.1093/arisup/akaa010
- Corrigan, P. W., & Watson, A. C. (2004). At issue: Stop the stigma: Call mental illness a brain disease. Schizophrenia Bulletin, 30(3), 477-479. https://doi.org/10.1093/oxfordjournals.schbul.a007095
- Cox, W. M., Klinger, E., & Fadardi, J. S. (2016). Nonconscious motivational influences on cognitive processes in addictive behaviors. In N. Heather & G. Segal (Eds.), Addiction and Choice (pp. 259-285). Oxford University Press. https://doi.org/10.1093/acprof:oso/9780198727224.003.0015
- Cummins, R. (1975). Functional analysis. The Journal of Philosophy, 72(20), 741-765. https://doi.org/10.2307/2024640
- Dar, R., Rosen-Korakin, N., Shapira, O., Gottlieb, Y., & Frenk, H. (2010). The craving to smoke in flight attendants: Relations with smoking deprivation, anticipation of smoking, and actual smoking. Journal of Abnormal Psychology, 119(1), 248-253. https://doi.org/10.1037/a0017778
- Davies, J. (2018). Addiction is not a brain disease. Addiction Research & Theory, 26(1), 1-2. https://doi.org/10.1080/16066359.2017.1321741
- Davies, W. (2016). Externalist psychiatry. Analysis, 76(3), 290-296. https://doi.org/10.1093/analys/anw038
- de Haan, S. (2020). An enactive approach to psychiatry. Philosophy, Psychiatry, & Psychology, 27(1), 3-25. https://doi.org/10.1353/ppp.2020.0001
- Dominus, S. (2019, February 19). Open Office. The New York Times Magazine.
- Edwards, C. (2009). Ethical decisions in the classification of mental conditions as mental illness. Philosophy, Psychiatry, & Psychology, 16(1), 73-90. https://doi.org/10.1353/ppp.0.0219
- Eitler, K., Bibok, A., & Telkes, G. (2022). Situs inversus totalis: A clinical review. International Journal of General Medicine, Volume 15, 2437-2449. https://doi.org/10.2147/IJGM.S295444
- Ersche, K. D., Williams, G. B., Robbins, T. W., & Bullmore, E. T. (2013). Meta-analysis of structural brain abnormalities associated with stimulant drug dependence and neuroimaging of addiction vulnerability and resilience. Current Opinion in Neurobiology, 23(4), 615-624. https://doi.org/10.1016/j.conb.2013.02.017
- Everitt, B. J., & Robbins, T. W. (2016). Drug addiction: Updating Actions to habits to compulsions ten years on. Annual Review of Psychology, 67(1), 23-50. https://doi.org/10.1146/annurev-psych-122414-033457
- Field, M., Heather, N., & Wiers, R. W. (2019). Indeed, not really a brain disorder: Implications for reductionist accounts of addiction. Behavioral and Brain Sciences, 42, e9. https://doi.org/10.1017/S0140525X18001024
- Fingarette, H. (1988). Heavy drinking: The myth of alcoholism as a disease. University of California Press. ark:/13960/t58d0j65h
- Flanagan, O. (2013). Phenomenal authority. In N. Levy (Ed.), Addiction and self-control (pp. 67-93). Oxford University Press. https://doi.org/10.1093/acprof:oso/9780199862580.003.0005
- Foddy, B., & Savulescu, J. (2010). A liberal account of addiction. Philosophy, Psychiatry, & Psychology, 17(1), 1-22. https://doi.org/10.1353/ppp.0.0282
- Garson, J. (2024). Brain disorders, dysfunctions, and natural selection: Commentary on Jefferson. Philosophical Psychology, 37(3), 558-569. https://doi.org/10.1080/09515089.2023.2232375
- Glackin, S. N., Roberts, T., & Krueger, J. (2021). Out of our heads: Addiction and psychiatric externalism. Behavioural Brain Research, 398, 112936. https://doi.org/10.1016/j.bbr.2020.112936
- Graham, G. (2010). The disordered mind: An introduction to philosophy of mind and mental illness. Taylor & Francis. https://doi.org/10.4324/9780203857861
- Hadland, S. E., Park, T. W., & Bagley, S. M. (2018). Stigma associated with medication treatment for young adults with opioid use disorder: A case series. Addiction Science & Clinical Practice, 13(1), 15. https://doi.org/10.1186/s13722-018-0116-2
- Hall, W., Carter, A., & Forlini, C. (2015). The brain disease model of addiction: Is it supported by the evidence and has it delivered on its promises? The Lancet Psychiatry, 2(1), 105-110. https://doi.org/10.1016/S2215-0366(14)00126-6
- Hammer, R. R., Dingel, M. J., Ostergren, J. E., Nowakowski, K. E., & Koenig, B. A. (2012). The experience of addiction as told by the addicted: Incorporating biological understandings into self-story. Culture, Medicine and Psychiatry, 36(4), 712-734. https://doi.org/10.1007/s11013-012-9283-x
- Hänninen, V., & Koski-Jännes, A. (1999). Narratives of recovery from addictive behaviours. Addiction, 94(12), 1837-1848. https://doi.org/10.1046/j.1360-0443.1999.941218379.x
- Hart, C. (2013). High price. Harper Perennial.
- Hart, C. (2017). Viewing addiction as a brain disease promotes social injustice. Nature Human Behaviour, 1(3), 0055. https://doi.org/10.1038/s41562-017-0055
- Heather, N. (2013). Is alcohol addiction usefully called a disease? Philosophy, Psychiatry, & Psychology, 20(4), 321-324. https://doi.org/10.1353/ppp.2013.0050
- Heather, N. (2017). Q: Is addiction a brain disease or a moral failing? A: Neither. Neuroethics, 10(1), 115-124. https://doi.org/10.1007/s12152-016-9289-0
- Heather, N., Field, M., Moss, A., & Satel, S. (Eds.) (2022). Evaluating the brain disease model of addiction. Routledge.
- Heilig, M., MacKillop, J., Martinez, D., Rehm, J., Leggio, L., & Vanderschuren, L. J. M. J. (2021). Addiction as a brain disease revised: Why it still matters, and the need for consilience. Neuropsychopharmacology, 46(10), 1715-1723. https://doi.org/10.1038/s41386-020-00950-y
- Heim, D. (2014). Addiction: Not just brain malfunction. Nature, 507, 40. https://doi.org/10.1038/507040e
- Henden, E. (2018). Addiction as a disorder of self-control. In H. Pickard & S. Ahmed (Eds.), The Routledge Handbook of Philosophy and Science of Addiction (pp. 45-53). Routledge.
- Heyman, G. M. (2009). Addiction: A disorder of choice. Harvard University Press.
- Heyman, G. M., & Mims, V. (2017). What addicts can teach us about addiction: A natural history approach. In N. Heather & G. Segal (Eds.), Addiction and choice (pp. 385-408). Oxford University Press. https://doi.org/10.1093/acprof:oso/9780198727224.003.0021
- Holden, T. (2012). Addiction is not a disease. Canadian Medical Association Journal, 184(6), 679. https://doi.org/10.1503/cmaj.112-2033
- Holton, R., & Berridge, K. (2013). Addiction between compulsion and choice. In Addiction and self-control. Oxford University Press. https://doi.org/10.1093/acprof:oso/9780199862580.003.0012
- Hyman, S. E. (2007). The neurobiology of addiction: Implications for voluntary control of behavior. American Journal of Bioethics, 7(1), 8-11. https://doi.org/10.1080/15265160601063969
- Jefferson, A. (2022). Are mental disorders brain disorders? Routledge.
- Juliano, L. M., & Brandon, T. H. (1998). Reactivity to instructed smoking availability and environmental cues: Evidence with urge and reaction time. Experimental and Clinical Psychopharmacology, 6(1), 45-53. https://doi.org/10.1037/1064-1297.6.1.45
- Kalivas, P. W., & Volkow, N. D. (2005). The neural basis of addiction: A pathology of motivation and choice. American Journal of Psychiatry, 162(8), 1403-1413. https://doi.org/10.1176/appi.ajp.162.8.1403
- Kavanagh, D. J., Andrade, J., & May, J. (2005). Imaginary relish and exquisite torture: The elaborated intrusion theory of desire. Psychological Review, 112(2), 446-467. https://doi.org/10.1037/0033-295X.112.2.446
- Kennett, J. (2013). Just say no? Addiction and the elements of self-control. In N. Levy (Ed.), Addiction and self-control (pp. 144-164). Oxford University Press. https://doi.org/10.1093/acprof:oso/9780199862580.003.0008
- Kvaale, E. P., Haslam, N., & Gottdiener, W. H. (2013). The ‘side effects’ of medicalization: A meta-analytic review of how biogenetic explanations affect stigma. Clinical Psychology Review, 33(6), 782-794. https://doi.org/10.1016/j.cpr.2013.06.002
- Leshner, A. I. (1997). Addiction is a brain disease, and it matters. Science, 278(5335), 45-47. https://doi.org/10.1126/science.278.5335.45
- Levy, N. (2013). Addiction is not a brain disease (and it matters). Frontiers in Psychiatry, 4. https://doi.org/10.3389/fpsyt.2013.00024
- Levy, N. (2014). Addiction as a disorder of belief. Biology and Philosophy, 29(3), 337-355. https://doi.org/10.1007/s10539-014-9434-2
- Lewis, M. (2015). The biology of desire: Why addiction is not a disease. Public Affairs. ark:/13960/s23dq7f9rfr
- Lewis, M. (2017). Addiction and the brain: Development, not disease. Neuroethics, 10(1), 7-18. https://doi.org/10.1007/s12152-016-9293-4
- Lie, A. K., Hansen, H., Herzberg, D., Mold, A., Jauffret-Roustide, M., Dussauge, I., Roberts, S. K., Greene, J., & Campbell, N. (2022). The harms of constructing addiction as a chronic, relapsing brain disease. American Journal of Public Health, 112(S2), S104–S108. https://doi.org/10.2105/AJPH.2021.306645
- Lilienfeld, S., & Marino, L. (1995). Mental disorder as a Roschian concept: A critique of Wakefield’s “harmful dysfunction” analysis. Journal of Abnormal Psychology, 104(3), 411-420. https://doi.org/10.1037/0021-843X.104.3.411
- Maguire, E. A., Gadian, D. G., Johnsrude, I. S., Good, C. D., Ashburner, J., Frackowiak, R. S. J., & Frith, C. D. (2000). Navigation-related structural change in the hippocampi of taxi drivers. Proceedings of the National Academy of Sciences, 97(8), 4398-4403. https://doi.org/10.1073/pnas.070039597
- Maiese, M. (2021). An enactivist reconceptualization of the medical model. Philosophical Psychology, 34(7), 962-988. https://doi.org/10.1080/09515089.2021.1940119
- McLellan, A. T., Lewis, D. C., O’Brien, C. P., & Kleber, H. D. (2000). Drug dependence, a chronic medical illness. JAMA, 284(13), 1689-1695. https://doi.org/10.1001/jama.284.13.1689
- Meurk, C., Carter, A., Partridge, B., Lucke, J., & Hall, W. (2014). How is acceptance of the brain disease model of addiction related to Australians’ attitudes towards addicted individuals and treatments for addiction? BMC Psychiatry, 14(1), 373. https://doi.org/10.1186/s12888-014-0373-x
- Millikan, R. (1984). Language, thought and other biological categories. The MIT Press.
- Murphy, D. (2009). Psychiatry and the concept of disease as pathology. In M. Broome & L. Bortolotti (Eds.), Psychiatry as Cognitive Neuroscience: Philosophical perspectives (pp. 103-118). Oxford University Press. https://doi.org/10.1093/med/9780199238033.003.0006
- Neander, K. (1991). Functions as selected effects: The conceptual analyst’s defense. Philosophy of Science, 58(2), 168-184. https://doi.org/10.1086/289610
- Palij, M., Rosenblum, A., Magura, S., Palij, M., Handelsman, L., & Stimmel, B. (1996). Daily cocaine use patterns: Effects of contextual and psychological variables. Journal of Addictive Diseases, 15(4), 13-37. https://doi.org/10.1300/J069v15n04_02
- Pescosolido, B. A., Martin, J. K., Long, J. S., Medina, T. R., Phelan, J. C., & Link, B. G. (2010). “A disease like any other”? A decade of change in public reactions to schizophrenia, depression, and alcohol dependence. American Journal of Psychiatry, 167(11), 1321-1330. https://doi.org/10.1176/appi.ajp.2010.09121743
- Pickard, H. (2016). Denial in addiction. Mind and Language, 31(3), 277-299. https://doi.org/10.1111/mila.12106
- Pickard, H. (2018). The puzzle of addiction. In H. Pickard & S. Ahmed (Eds.), The Routledge Handbook of Philosophy and Science of Addiction (pp. 9-22). Routledge.
- Pickard, H. (2022a). Addiction and the meaning of disease. In N. Heather, M. Field, A. Moss, & S. Satel (Eds.), Evaluating the brain disease model of addiction (pp. 321-338). Routledge.
- Pickard, H. (2022b). Is addiction a brain disease? A plea for agnosticism and heterogeneity. Psychopharmacology, 239(4), 993-1007. https://doi.org/10.1007/s00213-021-06013-4
- Pober, J. M. (2013). Addiction is not a natural kind. Frontiers in Psychiatry, 4(4), 123. https://doi.org/10.3389/fpsyt.2013.00123
- Redish, A. D., Jensen, S., & Johnson, A. (2008). A unified framework for addiction: Vulnerabilities in the decision process. Behavioral and Brain Sciences, 31(4), 415-487. https://doi.org/10.1017/S0140525X0800472X
- Rise, J., & Halkjelsvik, T. (2019). Conceptualizations of addiction and moral responsibility. Frontiers in Psychology, 10, 1483. https://doi.org/10.3389/fpsyg.2019.01483
- Roberts, T., Krueger, J., & Glackin, S. (2019). Psychiatry beyond the brain: Externalism, mental health, and autistic spectrum disorder. Philosophy, Psychiatry, & Psychology, 26(3), E-51-E-68. https://doi.org/10.1353/ppp.2019.0030
- Ross, D. (2020). Addiction is socially engineered exploitation of natural biological vulnerability. Behavioural Brain Research, 386, 112598. https://doi.org/10.1016/j.bbr.2020.112598
- Saloner, B., & Cook, B. L. (2013). Blacks and hispanics are less likely than whites to complete addiction treatment, largely due to socioeconomic factors. Health Affairs, 32(1), 135-145. https://doi.org/10.1377/hlthaff.2011.0983
- Satel, S., & Lilienfeld, S. (2014). Addiction and the brain-disease fallacy. Frontiers in Psychiatry, 4, 141. https://doi.org/10.3389/fpsyt.2013.00141
- Satel, S., & Lilienfeld, S. (2017, June 22). Calling it a “brain disease” makes addiction harder to treat. The Boston Globe.
- Schroeder, T., & Arpaly, N. (2013). Addiction and blameworthiness. In N. Levy (Ed.), Addiction and self-control (pp. 214–238). Oxford University Press. https://doi.org/10.1093/acprof:oso/9780199862580.003.0011
- Segal, A., Tiego, J., Parkes, L., Holmes, A. J., Marquand, A. F., & Fornito, A. (2024). Embracing variability in the search for biological mechanisms of psychiatric illness. Trends in Cognitive Sciences. https://doi.org/10.1016/j.tics.2024.09.010
- Segal, G. M. A. (2013). Alcoholism, disease, and insanity. Philosophy, Psychiatry, & Psychology, 20(4), 297-315. https://doi.org/10.1353/ppp.2013.0059
- Sinnott-Armstrong, W. (2013). Are addicts responsible? In N. Levy (Ed.), Addiction and self-control (pp. 122-143). Oxford University Press. https://doi.org/10.1093/acprof:oso/9780199862580.003.0007
- Sinnott-Armstrong, W., & Pickard, H. (2013). What is addiction? In K. W. M. Fulford, M. Davies, R. G. T. Gipps, G. Graham, J. Z. Sadler, G. Stanghellini, & T. Thornton (Eds.), The Oxford handbook of philosophy and psychiatry, vol. 1 (pp. 851-864). Oxford University Press. https://doi.org/10.1093/oxfordhb/9780199579563.013.0050
- Sisti, D., Young, M., & Caplan, A. (2013). Defining mental illnesses: Can values and objectivity get along? BMC Psychiatry, 13(1), 346. https://doi.org/10.1186/1471-244X-13-346
- Skinner, M. D., & Aubin, H. J. (2010). Craving’s place in addiction theory: Contributions of the major models. Neuroscience and Biobehavioral Reviews, 34(4), 606-623. https://doi.org/10.1016/j.neubiorev.2009.11.024
- Snoek, A. (2017a). Addiction, self-control and the self: An empirical, ethical study. Castricum.
- Snoek, A. (2017b). How to recover from a brain disease: Is addiction a disease, or is there a disease-like stage in addiction? Neuroethics, 10(1), 185-194. https://doi.org/10.1007/s12152-017-9312-0
- Sripada, C. (2022). Impaired control in addiction involves cognitive distortions and unreliable self-control, not compulsive desires and overwhelmed self-control. Behavioural Brain Research, 418, 113639. https://doi.org/10.1016/j.bbr.2021.113639
- Tiffany, S. T. (1990). A cognitive model of drug urges and drug-use behavior: Role of automatic and nonautomatic processes. Psychological Review, 97(2), 147-168. https://doi.org/10.1037/0033-295X.97.2.147
- Verhulst, B., Neale, M. C., & Kendler, K. S. (2015). The heritability of alcohol use disorders: A meta-analysis of twin and adoption studies. Psychological Medicine, 45(5), 1061-1072. https://doi.org/10.1017/S0033291714002165
- Volkow, N. D., & Koob, G. (2015). Brain disease model of addiction: Why is it so controversial? The Lancet Psychiatry, 2(8), 677-679. https://doi.org/10.1016/S2215-0366(15)00236-9
- Volkow, N. D., Koob, G. F., & McLellan, A. T. (2016). Neurobiologic advances from the brain disease model of addiction. New England Journal of Medicine, 374(4), 363-371. https://doi.org/10.1056/nejmra1511480
- Wakefield, J. C. (1992). The concept of mental disorder: On the boundary between biological facts and social values. American Psychologist, 47(3), 373-388. https://doi.org/10.1037/0003-066X.47.3.373
- Wakefield, J. C. (2020). Addiction from the harmful dysfunction perspective: How there can be a mental disorder in a normal brain. Behavioural Brain Research, 389, 112665. https://doi.org/10.1016/j.bbr.2020.112665
- Wakefield, J. C. (2021). Must social values play a role in the harm component of the harmful dysfunction analysis? Reply to Rachel Cooper. In L. Faucher & D. Forest (Eds.), Defining mental disorder: Jerome Wakefield and his critics (pp. 553-576). The MIT Press. https://doi.org/10.7551/mitpress/9949.003.0034
- World Health Organization. (2019). International Classification of Diseases, Eleventh Revision (ICD-11). https://icd.who.int/browse11
- Xiao, P., Dai, Z., Zhong, J., Zhu, Y., Shi, H., & Pan, P. (2015). Regional gray matter deficits in alcohol dependence: A meta-analysis of voxel-based morphometry studies. Drug and Alcohol Dependence, 153, 22-28. https://doi.org/10.1016/j.drugalcdep.2015.05.030
- Yang, L. H., Wong, L. Y., Grivel, M. M., & Hasin, D. S. (2017). Stigma and substance use disorders. Current Opinion in Psychiatry, 30(5), 378-388. https://doi.org/10.1097/YCO.0000000000000351